Silica-encapsulated DNA tracers for measuring aerosol distribution dynamics in real-world settings.

ABSTRACT: Aerosolized particles play a significant role in human health and environmental risk management. The global importance of aerosol-related hazards, such as the circulation of pathogens and high levels of air pollutants, have led to a surging demand for suitable surrogate tracers to investigate the complex dynamics of airborne particles in real-world scenarios. In this study, we propose a novel approach using silica particles with encapsulated DNA (SPED) as a tracing agent for measuring aerosol distribution indoors. In a series of experiments with a portable setup, SPED were successfully aerosolized, recaptured, and quantified using quantitative polymerase chain reaction (qPCR). Position dependency and ventilation effects within a confined space could be shown in a quantitative fashion achie

SUBMITTER: Luescher AM 

PROVIDER: S-EPMC9298268 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature