Prevalence and risk factors of cancer-related fatigue in childhood cancer survivors: A DCCSS LATER study.

ABSTRACT:

Background

Cancer-related fatigue is a debilitating late effect after treatment for childhood cancer. The prevalence of fatigue in childhood cancer survivors (CCSs) and associated factors for fatigue has varied widely in previous studies. Two important aspects of cancer-related fatigue, its severity and chronicity, are often not assessed. This study investigated the prevalence of, and risk factors for, severe chronic fatigue (CF) in a national cohort of Dutch CCSs.

Methods

In this study, 2810 CCSs (5-year survivors of all childhood malignancies diagnosed between 1963 and 2001 with a current age of 12-65 years) and 1040 sibling controls were included. CF was assessed with the Short Fatigue Questionnaire and was defined as a score ≥ 18 and persistence of fatigue for ≥6 months.

SUBMITTER: van Deuren S 

PROVIDER: S-EPMC9298343 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature