An integrated approach to the evaluation of patients with asymptomatic or minimally symptomatic hyperCKemia.

ABSTRACT:

Introduction/aims

Currently, there are no straightforward guidelines for the clinical and diagnostic management of hyperCKemia, a frequent and nonspecific presentation in muscle diseases. Therefore, we aimed to describe our diagnostic workflow for evaluating patients with this condition.

Methods

We selected 83 asymptomatic or minimally symptomatic patients with persistent hyperCKemia for participation in this Italian multicenter study. Patients with facial involvement and distal or congenital myopathies were excluded, as were patients with suspected inflammatory myopathies or predominant respiratory or cardiac involvement. All patients underwent a neurological examination and nerve conduction and electromyography studies. The first step of the investigation included a screen

SUBMITTER: Gemelli C 

PROVIDER: S-EPMC9298868 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature