Factors associated with relapse and recurrence of major depressive disorder in patients starting mindfulness-based cognitive therapy.

ABSTRACT:

Background

Mindfulness-based cognitive therapy (MBCT) is effective for relapse prevention in major depressive disorder (MDD). It reduces cognitive reactivity (CR) and rumination, and enhances self-compassion and mindfulness. Although rumination and mindfulness after MBCT are associated with relapse, the association of CR, rumination, self-compassion, and mindfulness with relapse before initiation of MBCT has never been investigated.

Methods

Data were drawn from two randomized controlled trials, including a total of 282 remitted MDD participants (≥3 depressive episodes) who had been using maintenance antidepressant medication (mADM) for at least 6 months before baseline. All participants were offered MBCT while either their mADM was maintained or discontinued after MBCT. CR,

SUBMITTER: de Klerk-Sluis JM 

PROVIDER: S-EPMC9298927 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature