Accounting for frailty and multimorbidity when interpreting high-sensitivity troponin I tests in oldest old.

ABSTRACT:

Background

Older patients evaluated in Emergency Departments (ED) for suspect Myocardial Infarction (MI) frequently exhibit unspecific elevations of serum high-sensitivity troponin I (hs-TnI), making interpretation particularly challenging for emergency physicians. The aim of this longitudinal study was to identify the interaction of multimorbidity and frailty with hs-TnI levels in older patients seeking emergency care.

Methods

A group of patients aged≥75 with suspected MI was enrolled in our acute geriatric ward immediately after ED visit. Multimorbidity and frailty were measured with Cumulative Illness Rating Scale (CIRS) and Clinical Frailty Scale (CFS), respectively. The association of hs-TnI with MI (main endpoint) was assessed by calculation of the Area Under the Recei

SUBMITTER: Ticinesi A 

PROVIDER: S-EPMC9299120 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature