Correlation between tear film lipid layer thickness and transepidermal water loss from the ocular area in patients with dry eye disease and in healthy controls.

ABSTRACT:

Purpose

This study aimed to evaluate the correlation between tear film lipid layer thickness and transepidermal water loss (TEWL) from the ocular area in patients with short tear break-up time (TBUT)-type dry eye and healthy controls.

Methods

This prospective study included 25 eyes of patients with short TBUT-type dry eye disease and 25 eyes of healthy controls.

Results

Tear film lipid layer thickness was measured using an interferometer, and TEWL from the ocular area was measured using a Tewameter TM300 with custom-made goggles. The correlation between tear film lipid layer thickness and TEWL was evaluated. Additionally, other parameters such as TBUT, Schirmer I score, ocular surface staining, the presence and type of meibomian gland dysfunction (MGD), ocular surface

SUBMITTER: Yoon DY 

PROVIDER: S-EPMC9299348 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature