A Novel Prognostic Score Including the CD4/CD8 for AIDS-Related Lymphoma.

ABSTRACT:

Background

A simple and clinically applicable prognostic scoring system for AIDS-related lymphoma (ARL) in the era of combination antiretroviral therapy (cART) is needed to better stratify patients' risks and to assist in the decision-making of therapeutic strategies.

Methods

We conducted a retrospective multicenter cohort study in 138 primary ARL patients over an 8-year period from 2013 to 2020. Survival curves were estimated using the Kaplan-Meier method. Univariate and multivariate Cox proportional hazard models were performed to identify the association between patient-, lymphoma-, and HIV-specific variables with progression-free survival (PFS) and overall survival (OS). The incremental prognostic value of novel inflammatory biomarkers in the International Prognostic Ind

SUBMITTER: Chen J 

PROVIDER: S-EPMC9299417 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature