Prostate cancer detection rate in men undergoing transperineal template-guided saturation and targeted prostate biopsy.

ABSTRACT:

Objectives

To compare prostate cancer (PCa) detection rate of transperineal template-guided saturation prostate biopsy (SBx) and multiparametric magnetic resonance imaging (mpMRI)/transrectal ultrasound fusion guided targeted biopsy (TBx). MATERIALS AND METHODS: We prospectively enrolled 392 men who underwent SBx and TBx in case of suspicious lesions from November 2016 to October 2019. Triggers for a biopsy were an elevated prostate-specific antigen (PSA) and/or positive digital rectal examination and only treatment naïve patients without a previous diagnosis of PCa were included. Study inclusion occurred before biopsy and a prebiopsy mpMRI was available in all men. SBx were taken from 20 different locations according to the modified Barzell zones. The primary endpoint was the dete

SUBMITTER: Kaufmann B 

PROVIDER: S-EPMC9299705 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature