Maternal prenatal psychological distress associates with offspring early-life wheezing - FinnBrain Birth Cohort.

ABSTRACT:

Background

Exposure to prenatal maternal psychological distress may contribute to the development of childhood atopic disorders. Little is known about the importance of distress severity and its duration for the risk. Our aim was to investigate how chronic maternal depressive and anxiety symptoms across gestation influence the risk of wheezing and eczema at child age 24 months.

Methods

The study population was drawn from the FinnBrain Birth Cohort Study, including 1305 mother-infant dyads followed across gestation until the child age of 24 months when the outcomes were mother-reported wheezing ever and doctor-diagnosed eczema. To investigate the risk of wheezing phenotypes, wheezing with and without eczema was separated. Maternal distress was assessed with the Edinburgh Post

SUBMITTER: Puosi E 

PROVIDER: S-EPMC9299775 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature