Moving persistence assessments into the 21st century: A role for weight-of-evidence and overall persistence.

ABSTRACT: Assessing the persistence of chemicals in the environment is a key element in existing regulatory frameworks to protect human health and ecosystems. Persistence in the environment depends on many fate processes, including abiotic and biotic transformations and physical partitioning, which depend on substances' physicochemical properties and environmental conditions. A main challenge in persistence assessment is that existing frameworks rely on simplistic and reductionist evaluation schemes that may lead substances to be falsely assessed as persistent or the other way around-to be falsely assessed as nonpersistent. Those evaluation schemes typically assess persistence against degradation half-lives determined in single-compartment simulation tests or against degradation levels measured in s

SUBMITTER: Redman AD 

PROVIDER: S-EPMC9299815 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature