Acute myocarditis following a third dose of COVID-19 mRNA vaccination in adults.

ABSTRACT:

Introduction

Myocarditis has been reported following the second dose of COVID-19 mRNA vaccination. Whether administration of additional doses of COVID-19 vaccines further increases the risk of myocarditis is unknown.

Methods

We included individuals who received one to three doses of BNT162b2 or mRNA-1273 mRNA vaccine between 12/14/2020 and 2/18/2022. Myocarditis within 21 days of vaccine administration was identified using electronic medical records. Incidence rate ratios were calculated by comparing the observed incidence with the expected incidence from the same population during a 365-day baseline period.

Results

Of 3,076,660 KPSC members who received at least one dose of COVID-19 mRNA vaccines, 2,916,739 (94.5%) received at least two doses, and 1,146,254 (47.0%) r

SUBMITTER: Simone A 

PROVIDER: S-EPMC9299985 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature