Modeling the population-level impact of opioid agonist treatment on mortality among people accessing treatment between 2001 and 2020 in New South Wales, Australia.

ABSTRACT:

Background and aims

The individual-level effectiveness of opioid agonist treatment (OAT) in reducing mortality is well established, but there is less evidence on population-level benefits. We use modeling informed with linked data from the OAT program in New South Wales (NSW), Australia, to estimate the impact of OAT provision in the community and prisons on mortality and the impact of eliminating excess mortality during OAT initiation/discontinuation.

Design

Dynamic modeling.

Setting and participants

A cohort of 49 359 individuals who ever received OAT in NSW from 2001 to 2018.

Measurements

Receipt of OAT was represented through five stages: (i) first month on OAT, (ii) short (1-9 months) and (iii) longer (9+ months) duration on OAT, (iv) first month following

SUBMITTER: Chaillon A 

PROVIDER: S-EPMC9299987 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature