Z-scores of fetal bladder size for antenatal differential diagnosis between posterior urethral valves and urethral atresia.

ABSTRACT:

Objective

To construct reference values for fetal urinary bladder distension in pregnancy and use Z-scores as a diagnostic tool to differentiate posterior urethral valves (PUV) from urethral atresia (UA).

Methods

This was a prospective cross-sectional study in healthy singleton pregnancies aimed at constructing nomograms of fetal urinary bladder diameter and volume between 15 and 35 weeks' gestation. Z-scores of longitudinal bladder diameter (LBD) were calculated and validated in a cohort of fetuses with megacystis with ascertained postnatal or postmortem diagnosis, collected from a retrospective, multicenter study. Correlations between anatomopathological findings, based on medical examination of the infant or postmortem examination, and fetal megacystis were established. T

SUBMITTER: Fontanella F 

PROVIDER: S-EPMC9299997 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature