External validation of prognostic models for chronic kidney disease among type 2 diabetes.

ABSTRACT:

Background

Various prognostic models have been derived to predict chronic kidney disease (CKD) development in type 2 diabetes (T2D). However, their generalisability and predictive performance in different populations remain largely unvalidated. This study aimed to externally validate several prognostic models of CKD in a T2D Thai cohort.

Methods

A nationwide survey was linked with hospital databases to create a prospective cohort of patients with diabetes (n = 3416). We undertook a systematic review to identify prognostic models and traditional metrics (i.e., discrimination and calibration) to compare model performance for CKD prediction. We updated prognostic models by including additional clinical parameters to optimise model performance in the Thai setting.

Results

SUBMITTER: Saputro SA 

PROVIDER: S-EPMC9300508 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature