An interactive time series image analysis software for dendritic spines.

ABSTRACT: Live fluorescence imaging has demonstrated the dynamic nature of dendritic spines, with changes in shape occurring both during development and in response to activity. The structure of a dendritic spine correlates with its functional efficacy. Learning and memory studies have shown that a great deal of the information stored by a neuron is contained in the synapses. High precision tracking of synaptic structures can give hints about the dynamic nature of memory and help us understand how memories evolve both in biological and artificial neural networks. Experiments that aim to investigate the dynamics behind the structural changes of dendritic spines require the collection and analysis of large time-series datasets. In this paper, we present an open-source software called SpineS for automa

SUBMITTER: Argunsah AO 

PROVIDER: S-EPMC9300710 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature