Gut Microbiota Composition and Metabolic Potential of Long-Living People in China.

ABSTRACT: Individuals with naturally long-life spans have been extensively studied to gain a greater understanding of what factors contribute to their overall health and ability to delay or avoid certain diseases. Our previous work showed that gut microbiota can be a new avenue in healthy aging studies. In the present study, a total of 86 Chinese individuals were assigned into three groups: the long-living group (90 + years old; n = 28), the elderly group (65-75 years old; n = 31), and the young group (24-48 years old; n = 27). These groups were used to explore the composition and functional genes in the microbiota community by using the metagenomic sequencing method. We found that long-living individuals maintained high diversity in gene composition and functional profiles. Fur

SUBMITTER: Zhang S 

PROVIDER: S-EPMC9300991 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature