First Report of bla _CTX-M-167, bla _SHV-1, and bla _TEM-1B Carrying Klebsiella pneumonia Showing High-Level Resistance to Carbapenems.

ABSTRACT: The prevalence of carbapenem-resistant Klebsiella pneumoniae is increasing. Although carbapenemase production is the main resistance mechanism of K. pneumonia to carbapenems, there are still some reports of non-carbapenemase-producing K.pneumoniae showing high-level resistance to carbapenems. In this study, we had also isolated a carbapenemase-negative carbapenem-resistant K. pneumoniae L204 from a patient with an asymptomatic urinary tract infection. Species identification was performed using MALDI-TOF MS, and carbapenemase-encoding genes were detected using both NG-test carba-5 and whole-genome sequencing. Antimicrobial susceptibility testing was performed by the broth microdilution method according to CLSI guidance. The results of antimicrobial susceptibility

SUBMITTER: Li S 

PROVIDER: S-EPMC9301006 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature