Abdominal Adipose Tissue Associates With Adiponectin and TNFα in Middle-Aged Healthy Men.

ABSTRACT:

Introduction

Adipokines are highly active biopeptides involved in glucose metabolism, insulin regulation and the development and progression of obesity and its associated diseases. It includes, among others, adiponectin, visfatin and tumor necrosis factor alpha (TNFα). The sources of adipokines and their associations with glucometabolic variables are not completely understood.

Aim

In this cross-sectional study, we aimed to investigate whether gene expression levels in subcutaneous adipose tissue (SAT) of selected adipokines and their corresponding circulating levels associate with the amount of AT in superficial (sSAT), deep (dSAT) and visceral AT (VAT), assessed by computed tomography (CT). Any association with glucometabolic variables were also explored.

Methods

In

SUBMITTER: Zaidi H 

PROVIDER: S-EPMC9301307 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature