Unknown

Dataset Information

0

Indole Diketopiperazine Alkaloids Isolated From the Marine-Derived Fungus Aspergillus chevalieri MCCC M23426.

ABSTRACT: Two new indole diketopiperazines (1-2) obtained from the fermentation culture of a deep-sea-derived fungus Aspergillus chevalieri MCCC M23426, were characterized, together with nine biogenetic related compounds (3-11). The structures of 1-2 were assigned based on NMR, MS, NMR calculation, DP4+ analysis, and ECD calculation. The bioactive assay showed that compounds 1, 5-7 significantly inhibited the growth of Staphylococcus aureus. Meanwhile, compound 8 potently reduced the cell viability of gastric cancer cell MKN1 with an IC50 value of 4.6 μM.

SUBMITTER: Lv D 

PROVIDER: S-EPMC9301495 | biostudies-literature |

REPOSITORIES: biostudies-literature

Json Xml

Similar Datasets

Unknown Bioactive Indole Diketopiperazine Alkaloids from the Marine Endophytic Fungus Aspergillus sp. YJ191021.
| S-EPMC8002477 | biostudies-literature
Unknown Three New Quinazoline-Containing Indole Alkaloids From the Marine-Derived Fungus <i>Aspergillus</i> sp. HNMF114.
| S-EPMC8206283 | biostudies-literature
Unknown New Prenylated Indole Homodimeric and Pteridine Alkaloids from the Marine-Derived Fungus Aspergillus austroafricanus Y32-2.
| S-EPMC7916005 | biostudies-literature
Unknown Marine Fungus Aspergillus chevalieri TM2-S6 Extract Protects Skin Fibroblasts from Oxidative Stress.
| S-EPMC7551392 | biostudies-literature
Unknown Isolation of notoamide E, a key precursor in the biosynthesis of prenylated indole alkaloids in a marine-derived fungus, Aspergillus sp.
| S-EPMC2671082 | biostudies-literature
Unknown Bioactive Novel Indole Alkaloids and Steroids from Deep Sea-Derived Fungus Aspergillus fumigatus SCSIO 41012.
| S-EPMC6225233 | biostudies-literature
Unknown Aniquinazolines A-D, four new quinazolinone alkaloids from marine-derived endophytic fungus Aspergillus nidulans.
| S-EPMC3736446 | biostudies-literature
Unknown Cytotoxic Polyketides Isolated from the Deep-Sea-Derived Fungus Penicillium chrysogenum MCCC 3A00292.
| S-EPMC6950755 | biostudies-literature
Unknown Reprogramming Escherichia coli for the production of prenylated indole diketopiperazine alkaloids.
| S-EPMC6592928 | biostudies-literature
Unknown Isolation, Structural Characterization and Antidiabetic Activity of New Diketopiperazine Alkaloids from Mangrove Endophytic Fungus Aspergillus sp. 16-5c.
| S-EPMC8304462 | biostudies-literature