Adherence of ticagrelOr in real world patients with aCute coronary syndrome: The AD-HOC study.

ABSTRACT:

Background

Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor antagonist is the cornerstone of therapy in patients with acute coronary syndrome (ACS). Adherence to medical therapy is an important issue, as premature DAPT discontinuation increases the risk of new ischemic events. The aim of the present observational prospective multicenter study was to evaluate in the real-world incidence and discontinuation patterns of ticagrelor during the first 12 months after ACS.

Methods

We analyzed 431 ACS patients, discharged with ticagrelor, by 7 Italian centers. The primary end-point was the incidence of cessation of ticagrelor up to 12 months from the index event.

Results

Definitive ticagrelor cessations occurred in 52 patients (12.1%), of which 35 were discon

SUBMITTER: Fiocca L 

PROVIDER: S-EPMC9301572 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature