Rates of Medically Attended RSV Among US Adults: A Systematic Review and Meta-analysis.

ABSTRACT:

Background

Adult respiratory syncytial virus (RSV) vaccines are in the late stages of development. A comprehensive synthesis of adult RSV burden is needed to inform public health decision-making.

Methods

We performed a systematic review and meta-analysis of studies describing the incidence of medically attended RSV (MA-RSV) among US adults. We also identified studies reporting nasopharyngeal (NP) or nasal swab reverse transcription polymerase chain reaction (RT-PCR) results with paired serology (4-fold-rise) or sputum (RT-PCR) to calculate RSV detection ratios quantifying improved diagnostic yield after adding a second specimen type (ie, serology or sputum).

Results

We identified 14 studies with 15 unique MA-RSV incidence estimates, all based on NP or nasal swab RT-PC

SUBMITTER: McLaughlin JM 

PROVIDER: S-EPMC9301578 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature