Association of Visit-to-Visit Variability in Fasting Plasma Glucose with Digestive Cancer Risk.

ABSTRACT:

Background and aims

The aim of this study is to investigate the association between visit-to-visit variability in fasting plasma glucose (FPG) and the risk of digestive cancers among individuals with and without diabetes.

Methods

Using data from Kailuan cohort, a prospective population-based study, individuals who had at least two measurements of FPG between 2006 and 2012 without prior cancer were included in this study. Four indexes of variability were used, including standard deviation (SD), coefficient of variation (CV), variability independent of the mean (VIM), and average successive variability (ARV). Cox regression was used to evaluate the relationship between the quartiles of FPG variability and digestive cancers.

Results

A total of 98,161 individuals were stu

SUBMITTER: Zhang N 

PROVIDER: S-EPMC9301759 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature