The multisystemic effects of oral appliance therapy for obstructive sleep apnea: A narrative review.

ABSTRACT: Obstructive sleep apnea (OSA) is a chronic condition accompanied by repeated obstruction of the upper airway during sleep despite respiratory efforts, resulting in intermittent hypoxemia, altered sleep structure, and sympathetic activation. Previous studies have shown a significant association between OSA and general health issues such as cardiovascular diseases, endocrine disorders, neurocognitive function decline, and poor quality of life. Continuous positive airway pressure (CPAP) has been considered as the first line treatment for OSA. However, accumulating evidence supports the role of oral appliance (OA) therapy, including mandibular advancement devices, as an alternative option for snoring and OSA patients who do not comply with or refuse CPAP usage. Despite a generally favorable ou

SUBMITTER: Kim HY 

PROVIDER: S-EPMC9302291 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature