Canavanine versus arginine: Prospects for cell-penetrating peptides.

ABSTRACT: Octanol-water partitioning experiments in the presence of carboxylate-, phosphate-, and sulfate-containing anionic lipids revealed that Ac-Cav-NH₂ (where Cav refers to δ-oxa-arginine) partitions less into octanol than does Ac-Arg-NH₂, suggesting that a cell-penetrating peptide based on canavanine would be relatively ineffective.

SUBMITTER: Calabretta LO 

PROVIDER: S-EPMC9302579 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature