What is the added value of patch testing with 30 fragrance allergens in addition to the European Baseline series?

ABSTRACT:

Background

Patch testing with the fragrance allergy markers in the European baseline series (EBS) does not identify all patients with fragrance allergy. Hydroperoxides of linalool and limonene have been shown to be useful allergens in detecting fragrance sensitization.

Objectives

To evaluate the added value of testing with 30 fragrance allergens in addition to the EBS.

Methods

All patients with suspected fragrance allergy who underwent patch testing at the Amsterdam University Medical Centers between November 2019 and January 2021 to the EBS and fragrance series were included.

Results

Of 323 patients tested, 162 (50.2%) were found to be fragrance sensitized. The most sensitizing single allergens were the hydroperoxides of linalool (1.0 and 0.5% pet.) and limone

SUBMITTER: Krijl RC 

PROVIDER: S-EPMC9302649 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature