Bone marrow involvement in patients with metastatic castration sensitive prostate cancer.

ABSTRACT:

Introduction

The clinical significance of bone marrow (BM) metastasis in prostate cancer as well as impact on oncological prognosis is unclear. We aim to assess the prevalence and clinical outcomes of BM metastasis at initial presentation of metastatic castrate sensitive prostate cancer (CSPC).

Patients and methods

Retrospective chart review of newly diagnosed metastatic CSPC patients was performed with collection of clinicopathologic and radiologic characteristics. Descriptive univariate and multivariate analysis was performed as well as survival measures (OS and PFS), which was done using the Kaplan-Meier survival and the Log-rank test.

Results

189 patients were eligible, of which, eleven patients (6%) had biopsy proven BM involvement at diagnosis. There was a trend

SUBMITTER: Shahait M 

PROVIDER: S-EPMC9302741 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature