Age-related twin-peak prevalence profiles of H. pylori infection, gastritis, GIN and gastric cancer: Analyses of 70,534 patients with gastroscopic biopsies.

ABSTRACT:

Objectives

H. pylori (Hp) infection has been indicated in the pathogenesis of gastric diseases including gastric cancer (GC). This study aimed at exploring the relationships between Hp infection and gastric diseases including GC in a large dataset of routine patients undergoing gastroscopy.

Methods

From November 2007 to December 2017, 70,534 first-time visiting patients aged 18-94 years with gastroscopic biopsies were histologically diagnosed and analyzed. Patients' data were entered twice in an Excel spreadsheet database and analyzed using the SPSS (version 22.0) software package and statistical significance was defined as P<0.05 for all analyses.

Results

The first interesting observation was age-related twin-peak prevalence profiles (TPPs) for Hp infection, gastriti

SUBMITTER: Xu MQ 

PROVIDER: S-EPMC9302749 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature