Septal flash correction with His-Purkinje pacing predicts echocardiographic response in resynchronization therapy.

ABSTRACT:

Background

His-Purkinje conduction system pacing (HPCSP) has been proposed as an alternative to Cardiac Resynchronization Therapy (CRT); however, predictors of echocardiographic response have not been described in this population. Septal flash (SF), a fast contraction and relaxation of the septum, is a marker of intraventricular dyssynchrony.

Methods

The study aimed to analyze whether HPCSP corrects SF in patients with CRT indication, and if correction of SF predicts echocardiographic response. This retrospective analysis of prospectively collected data included 30 patients. Left ventricular ejection fraction (LVEF) was measured with echocardiography at baseline and at 6-month follow-up. Echocardiographic response was defined as increase in five points in LVEF.

Results

SUBMITTER: Pujol-Lopez M 

PROVIDER: S-EPMC9303224 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature