Cell death induced by mycotoxin fumonisin B₁ is accompanied by oxidative stress and transcriptional modulation in Arabidopsis cell culture.

ABSTRACT:

Key message

Fumonisin B₁ induces rapid programmed cell death in Arabidopsis cells, oxidative and nitrosative bursts, and differentially modulates cell death responsive genes. Glutathione is the main antioxidant involved in the stress response. Fumonisin B₁ (FB₁) is a fungal toxin produced by Fusarium spp. able to exert pleiotropic toxicity in plants. FB₁ is known to be a strong inducer of the programmed cell death (PCD); however, the exact mechanism underling the plant-toxin interactions and the molecular events that lead to PCD are still unclear. Therefore, in this work, we provided a comprehensive investigation of the response of the model organism Arabidopsis thaliana at the nuclear, transcriptional, and biochemical level after the tre

SUBMITTER: Lanubile A 

PROVIDER: S-EPMC9304057 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature