Relationship between lung function and exhaled volatile organic compounds in healthy infants.

ABSTRACT:

Objective

The aim of this study is to assess, for the first time, the relationship between the volatilome and lung function in healthy infants, which may be of help for the early detection of certain respiratory diseases. Lung function tests are crucial in chronic respiratory diseases diagnosis. Moreover, volatile organic compounds (VOCs) analysis in exhaled breath is a noninvasive technique that enables the monitorization of oxidative stress, typical of some forms of airway inflammation.

Methods

Lung function was studied in 50 healthy infants of 3-8 months of age and the following parameters were obtained: forced vital capacity (FVC), forced expiratory volume at 0.5 s (FEV_0.5 ), forced expiratory flow at 75% of FVC (FEF₇₅ ), forced expiratory flow at 2

SUBMITTER: Sola-Martinez RA 

PROVIDER: S-EPMC9304127 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature