Sardine oil loaded vanillic acid grafted chitosan microparticles improves the in vivo antioxidant, haematological and lipid profile.

ABSTRACT: Oxidative stability of fish oil supplements poses a considerable health risk which can be prevented by novel delivery systems. A newly developed formulation of microencapsulated sardine oil showed excellent oxidative stability in vitro. The present study's objective is to evaluate the new formulation in vivo as a potential new supplement which may improve antioxidant, haematological, and lipid profile. The optimisation of the sardine oil loaded microparticles (SO-M) and the characterisation have been presented briefly. The SO-M formulation was fed to male albino rats for two months. Following the feeding experiment, haemoglobin content, platelet and RBC count were assessed in the control and treated group. Similarly, levels of serum cholesterol, HDL, LDL, triglycerides, and metabolic enzym

SUBMITTER: Vishnu KV 

PROVIDER: S-EPMC9304486 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature