New Insights on Bone Tissue and Structural Muscle-Bone Unit in Constitutional Thinness.

ABSTRACT: While few studies pointed out low bone mineral densities in constitutionally thin women, little is known about potential explanations. The objective was to further explore bone architecture in both women and men with constitutional thinness to investigate their mechanical muscle-bone coupling (or uncoupling). Thirty constitutionally thin people and 31 normal weight controls participated in the study. Body composition, hip structural analysis, and trabecular bone score were assessed by dual-energy X-ray absorptiometry, bone architecture using high-resolution peripheral quantitative computed tomography, and muscle explorations through histological staining on muscle biopsies. Thirty-two out of the 48 indexes relative to density, geometry, texture, and architecture of bones were found signifi

SUBMITTER: Bailly M 

PROVIDER: S-EPMC9305386 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature