Risk assessment of a new bioinformatics evaluation of the insertion sites of genetically modified soybean event 40-3-2.

ABSTRACT: Genetically modified (GM) soybean 40-3-2 expresses a 5-enolpyruvylshikimate-3-phosphate synthase protein from Agrobacterium sp. strain CP4 (CP4 EPSPS), which confers tolerance to glyphosate. This event was previously assessed by the GMO Panel as a single event and as part of a two-event stack and was found to be as safe as its conventional counterparts and other appropriate comparators with respect to potential effects on human and animal health and the environment. On September 2021, the European Commission requested EFSA to evaluate a new bioinformatics study which revealed predicted genomic deletions at the insertion sites using the available soybean reference genome. Considering the variability of the soybean genome, with a number of structural variants such as presence/absence

SUBMITTER: EFSA Panel on Genetically Modified Organisms (GMO) 

PROVIDER: S-EPMC9305392 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature