α-Dioxygenases (α-DOXs): Promising Biocatalysts for the Environmentally Friendly Production of Aroma Compounds.

ABSTRACT: Fatty aldehydes (FALs) can be derived from fatty acids (FAs) and related compounds and are frequently used as flavors and fragrances. Although chemical methods have been conventionally used, their selective biotechnological production aiming at more efficient and eco-friendly synthetic routes is in demand. α-Dioxygenases (α-DOXs) are heme-dependent oxidative enzymes biologically involved in the initial step of plant FA α-oxidation during which molecular oxygen is incorporated into the C_α -position of a FA (C_n ) to generate the intermediate FA hydroperoxide, which is subsequently converted into the shortened corresponding FAL (C_n-1 ). α-DOXs are promising biocatalysts for the flavor and fragrance industries, they do not require NAD(P)H as cofactors or redox

SUBMITTER: Kim IJ 

PROVIDER: S-EPMC9305512 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature