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ABSTRACT:
SUBMITTER: Cieslik P
PROVIDER: S-EPMC9305554 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Cieslik Patrick P Comba Peter P Dittmar Benedikt B Ndiaye Daouda D Tóth Éva É Velmurugan Gunasekaran G Wadepohl Hubert H
Angewandte Chemie (International ed. in English) 20220120 10
While Mn<sup>II</sup> complexes meet increasing interest in biomedical applications, ligands are lacking that enable high Mn<sup>II</sup> complex stability and selectivity vs. Zn<sup>II</sup> , the most relevant biological competitor. We report here two new bispidine derivatives, which provide rigid and large coordination cavities that perfectly match the size of Mn<sup>II</sup> , yielding eight-coordinate Mn<sup>II</sup> complexes with record stabilities. In contrast, the smaller Zn<sup>II</sup ...[more]