Lysozyme crystallization in hydrogel media under ultrasound irradiation.

ABSTRACT: Sonocrystallization implies the application of ultrasound radiation to control the nucleation and crystal growth depending on the actuation time and intensity. Its application allows to induce nucleation at lower supersaturations than required under standard conditions. Although extended in inorganic and organic crystallization, it has been scarcely explored in protein crystallization. Now, that industrial protein crystallization is gaining momentum, the interest on new ways to control protein nucleation and crystal growth is advancing. In this work we present the development of a novel ultrasound bioreactor to study its influence on protein crystallization in agarose gel. Gel media minimize convention currents and sedimentation, favoring a more homogeneous and stable conditions to study t

SUBMITTER: Savchenko M 

PROVIDER: S-EPMC9305616 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature