Real-world effectiveness of pharmacological treatments of opioid use disorder in a national cohort.

ABSTRACT:

Aim

To investigate the real-world effectiveness of pharmacological treatments (buprenorphine, methadone) of opioid use disorder (OUD).

Design

A nation-wide, register-based cohort study.

Setting

Sweden.

Participants

All residents aged 16-64 years living in Sweden using OUD medication from July 2005 to December 2016 (n = 5757, 71.8% men) were identified from registers of prescriptions, inpatient and specialized outpatient care, causes of death, sickness absence and disability pensions.

Measurements

Main outcome: hospitalization due to OUD.

Secondary outcomes

hospitalization due to any cause; death due to all, natural and external causes. Mortality was analyzed with between-individual multivariate-adjusted Cox hazards regression model. Recurrent outc

SUBMITTER: Heikkinen M 

PROVIDER: S-EPMC9305765 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature