Choice of oral anticoagulant prescribed by general practices in Wales: Application of Dirichlet regression and linked data.

ABSTRACT:

Aims

There has been sustained growth in the prescribing of direct oral anticoagulants (OACs) in primary care in the UK. Given the different indications, properties and prices of OACs, variation between prescribers is expected; however, a high level of variation may be evidence of inappropriate or suboptimal prescribing. This study examined the variation in the relative use of OACs in primary care in Wales.

Methods

Data on total defined daily doses of all community-dispensed OACs in 2019 were linked at the GP practice level with disease registers, patient demographic data and GP and patient numbers. The relative use of each OAC, as a fraction of all OACs prescribed, was analysed using Dirichlet regression to quantify the association between prescribing patterns and practice a

SUBMITTER: Hill-McManus D 

PROVIDER: S-EPMC9305862 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature