Changes in mean systemic filling pressure as an estimate of hemodynamic response to anesthesia induction using propofol.

ABSTRACT:

Background

Even a small change in the pressure gradient between the venous system and the right atrium can have significant hemodynamic effects. Mean systemic filling pressure (MSFP) is the driving force of the venous system. As a result, MSFP has a significant effect on cardiac output. We aimed to test the hypothesis that the hemodynamic instability during induction of general anesthesia by intravenous propofol administration is caused by changes in MSFP.

Methods

We prospectively collected data from 15 patients undergoing major surgery requiring invasive hemodynamic monitoring. Hemodynamic parameters, including MSFP, were measured before and after propofol administration and following intubation, using venous return curves at a no-flow state induced by a pneumatic tournique

SUBMITTER: Zucker M 

PROVIDER: S-EPMC9306094 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature