Grey matter changes on brain MRI in subjective cognitive decline: a systematic review.

ABSTRACT:

Introduction

People with subjective cognitive decline (SCD) report cognitive deterioration. However, their performance in neuropsychological evaluation falls within the normal range. The present study aims to analyse whether structural magnetic resonance imaging (MRI) reveals grey matter changes in the SCD population compared with healthy normal controls (HC).

Methods

Parallel systematic searches in PubMed and Web of Science databases were conducted, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Quality assessment was completed using the Newcastle-Ottawa Scale (NOS).

Results

Fifty-one MRI studies were included. Thirty-five studies used a region of interest (ROI) analysis, 15 used a voxel-based morphometry (VBM) a

SUBMITTER: Arrondo P 

PROVIDER: S-EPMC9306106 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature