Apparent diffusion coefficient values in Modic changes - interobserver reproducibility and relation to Modic type.

ABSTRACT:

Background

Modic Changes (MCs) in the vertebral bone marrow were related to back pain in some studies but have uncertain clinical relevance. Diffusion weighted MRI with apparent diffusion coefficient (ADC)-measurements can add information on bone marrow lesions. However, few have studied ADC measurements in MCs. Further studies require reproducible and valid measurements. We expect valid ADC values to be higher in MC type 1 (oedema type) vs type 3 (sclerotic type) vs type 2 (fatty type). Accordingly, the purpose of this study was to evaluate ADC values in MCs for interobserver reproducibility and relation to MC type.

Methods

We used ADC maps (b 50, 400, 800 s/mm²) from 1.5 T lumbar spine MRI of 90 chronic low back pain patients with MCs in the AIM (Antibiotics In

SUBMITTER: Dagestad MH 

PROVIDER: S-EPMC9306145 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature