Effects of endoscopic injection sclerotherapy for esophagogastric varices on portal hemodynamics and liver function.

ABSTRACT:

Objectives

To identify patients suitable for endoscopic injection sclerotherapy (EIS) by evaluating their portal hemodynamics and liver function.

Methods

We selected 58 patients with esophagogastric varices (EGV) and liver cirrhosis (LC) related to either hepatitis C virus (C) (n = 19), hepatitis B virus (n = 2), alcohol (AL) (n = 20), C + AL (n = 6), non-alcoholic steatohepatitis (n = 6), others (n = 3), or non-LC (n = 2). All patients underwent EIS. We measured their portal venous tissue blood flow (PVTBF) and hepatic arterial tissue blood flow (HATBF) using xenon computed tomography before and after EIS. We classified them into increased group and decreased group according to the PVTBF to identify the predictors that contribute to PVTBF increase post-EIS.

Results

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SUBMITTER: Shigefuku R 

PROVIDER: S-EPMC9306194 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature