Metagenomic insights into the microbe-mediated B and K₂ vitamin biosynthesis in the gastrointestinal microbiome of ruminants.

ABSTRACT:

Background

B and K₂ vitamins, essential nutrients in host metabolism, can be synthesized by the rumen microbiome in ruminants and subsequently absorbed by the host. However, the B and K₂ vitamin biosynthesis by the whole gastrointestinal microbiome and their abundances in different dietary strategies are largely unknown. Here, we reanalyzed our previous large-scale metagenomic data on the gastrointestinal microbiome of seven ruminant species and recruited 17,425 nonredundant microbial genomes from published datasets to gain a comprehensive understanding of the microbe-mediated B and K₂ vitamin biosynthesis in ruminants.

Results

We identified 1,135,807 genes and 167 enzymes involved in B and K₂ vitamin biosynthesis. Our results indi

SUBMITTER: Jiang Q 

PROVIDER: S-EPMC9306216 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature