Investigation of healthcare-associated COVID-19 in a large French hospital group by whole-genome sequencing.

ABSTRACT:

Objectives

Despite the quick implementation of infection prevention and control procedures and the use of personal protective equipment within healthcare facilities, many cases of nosocomial COVID-19 transmission have been reported. We aimed to estimate the frequency and impact of healthcare-associated COVID-19 (HA-COVID-19) and evaluate the contribution of whole-genome sequencing (WGS) in cluster investigation.

Methods

We estimated the frequency and mortality of HA-COVID-19 infections from September 1 to November 30, 2020, with a focus on the evolution of hospitalized community-associated COVID-19 (CA-COVID-19) cases and cases detected among healthcare workers (HCWs) within the Sorbonne University Hospital Group (Paris, France). We thoroughly examined 12 clusters through ep

SUBMITTER: Leducq V 

PROVIDER: S-EPMC9306220 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature