Maternal early-pregnancy ferritin and offspring neurodevelopment: A prospective cohort study from gestation to school age.

ABSTRACT:

Background

Iron plays a role in many key processes in the developing brain. During pregnancy, iron supplementation is widely recommended to prevent and treat iron deficiency; however, the prevalence of iron deficiency and the risk of iron overload vary greatly between populations. Evidence on the role of high levels of maternal ferritin, a storage iron marker during pregnancy in relation to offspring neurodevelopment is lacking.

Objective

Our main objective was to examine if maternal ferritin levels during pregnancy are associated with child cognitive and motor abilities.

Methods

We included Dutch mother-child dyads from the prospective population-based Generation R Study, born in 2002-2006. We compared children whose mothers had high (standard deviation score >+1) or

SUBMITTER: Sammallahti S 

PROVIDER: S-EPMC9306570 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature