Epidemiology of cardiovascular death in kidney failure: An Australian and New Zealand cohort study using data linkage.

ABSTRACT:

Aim

Cardiovascular mortality risk evolves over the lifespan of kidney failure (KF), as patients develop comorbid disease and transition between treatment modalities. Absolute cardiovascular death rates would help inform clinical practice and health-care provision, but are not well understood across a continuum of dialysis and transplant states. We aimed to characterize cardiovascular death across the natural history of KF using a lifespan approach.

Methods

We performed a population-based cohort study of incident patients commencing kidney replacement therapy in Australia and New Zealand. Cardiovascular deaths were identified using data linkage to national death registers. We estimated the probability of death and kidney transplant using multi-state models, and calculated rat

SUBMITTER: Khou V 

PROVIDER: S-EPMC9306651 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature