Formation of Temporary Negative Ions and Their Subsequent Fragmentation upon Electron Attachment to CoQ₀ and CoQ₀ H₂.

ABSTRACT: Ubiquinone molecules have a high biological relevance due to their action as electron carriers in the mitochondrial electron transport chain. Here, we studied the dissociative interaction of free electrons with CoQ₀ , the smallest ubiquinone derivative with no isoprenyl units, and its fully reduced form, 2,3-dimethoxy-5-methylhydroquinone (CoQ₀ H₂ ), an ubiquinol derivative. The anionic products produced upon dissociative electron attachment (DEA) were detected by quadrupole mass spectrometry and studied theoretically through quantum chemical and electron scattering calculations. Despite the structural similarity of the two studied molecules, remarkably only a few DEA reactions are present for both compounds, such as abstraction of a neutral hydrogen atom o

SUBMITTER: Ameixa J 

PROVIDER: S-EPMC9306667 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature