Ontology highlight
ABSTRACT:
SUBMITTER: Bader CD
PROVIDER: S-EPMC9306752 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Bader Chantal D CD Panter Fabian F Garcia Ronald R Tchesnokov Egor P EP Haid Sibylle S Walt Christine C Spröer Cathrin C Kiefer Alexander F AF Götte Matthias M Overmann Jörg J Pietschmann Thomas T Müller Rolf R
Chemistry (Weinheim an der Bergstrasse, Germany) 20220122 10
Structure elucidation and total synthesis of five unprecedented terpenoid-alkaloids, the sandacrabins, are reported, alongside with the first description of their producing organism Sandaracinus defensii MSr10575, which expands the Sandaracineae family by only its second member. The genome sequence of S. defensii as presented in this study was utilized to identify enzymes responsible for sandacrabin formation, whereby dimethylbenzimidazol, deriving from cobalamin biosynthesis, was identified as ...[more]