The innate immune stimulant Amplimune® is safe to administer to young feedlot cattle.

ABSTRACT:

Background

Infectious disease has a significant impact on livestock production. Availability of alternatives to antibiotics to prevent and treat disease is required to reduce reliance on antibiotics while not impacting animal welfare. Innate immune stimulants, such as mycobacterium cell wall fractions (MCWF), are used as alternatives to antibiotics for the treatment and prevention of infectious disease in a number of species including cattle, horses and dogs. This study aimed to evaluate the safety of Amplimune®, an MCWF-based immune stimulant, for weaner Angus cattle.

Methods

On day -1 and 0, sixty mixed-sex Angus weaner cattle were transported for 6 h before being inducted and housed in a large single pen, simulating feedlot induction conditions. The cattle were assigned t

SUBMITTER: Alexander AL 

PROVIDER: S-EPMC9306767 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature