Assessing Alkali-Metal Effects in the Structures and Reactivity of Mixed-Ligand Alkyl/Alkoxide Alkali-Metal Magnesiates.

ABSTRACT: Advancing the understanding of using alkali-metal alkoxides as additives to organomagnesium reagents in Mg-Br exchange reactions, a homologous series of mixed-ligand alkyl/alkoxide alkali-metal magnesiates [MMg(CH₂ SiMe₃ )₂ (dmem)]₂ [dmem=2-{[2-(dimethylamino)ethyl]methylamino} ethoxide; M=Li, 1; Na, 2; (THF)K, 3] has been prepared. Structural and spectroscopic studies have established the constitutions of these heteroleptic/heterometallic species, which are retained in arene solution. Evaluation of their reactivity towards 2-bromoanisole has uncovered a marked alkali-metal effect with potassium magnesiate 3 being the most efficient of the three ate reagents. Studies probing the constitution of the exchange product from this reaction suggest that

SUBMITTER: Judge NR 

PROVIDER: S-EPMC9306829 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature